𝔖 Bobbio Scriptorium
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Cancer biology: Heritable fragile sites in cancer

✍ Scribed by LeBeau, Michelle M.; Rowley, Janet D.

Book ID
109735099
Publisher
Nature Publishing Group
Year
1984
Tongue
English
Weight
267 KB
Volume
308
Category
Article
ISSN
0028-0836

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## Abstract Common fragile sites (CFS) are large, genomically unstable regions, which are hot‐spots for deletions and other alterations, especially in cancer cells. Several have been shown to contain genes that span large genomic regions, such as __FHIT__ (1.5 Mb), __WWOX__ (1.0 Mb), __GRID2__ (1.3