𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Bromine-promoted cyclization of an olefinic α-aminonitrile: A practical synthesis of 5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (ADCI)

✍ Scribed by Javier Gonzalez; F.Ivy Carroll


Book ID
104255799
Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
192 KB
Volume
37
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


ChemInform Abstract: Bromine-Promoted Cy
✍ J. GONZALEZ; F. I. CARROLL 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 33 KB 👁 1 views

Bromine-Promoted Cyclization of an Olefinic α-Aminonitrile: A Practical Synthesis of 5-Aminocarbonyl-10,11-dihydro-5H-dibenzo(a,d) cyclohepten-5,10-imine (ADCI). -ADCI (VII) is a selective, lowaffinity noncompetitive antagonist of the NMDA receptor showing promising anticonvulsant activity. In the

Synthesis of 11C-labeled (±)-5-methyl-10
✍ Dale O. Kiesewetter; Ronald D. Finn; Kenner C. Rice; James A. Monn 📂 Article 📅 1990 🏛 Elsevier Science ⚖ 367 KB

The synthesis of C5 labeled (+-)-5-[11C]methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten- 5,10-imine [(+-)-[11C]MK801] has been accomplished via alkylation of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine-N-t- butylformamidine [(+-)-5-des-methyl MK801 formamidine). The 11C labeling is ac