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Arene Chromium and Manganese Tricarbonyl Analogs of the PCP Receptor Ligands 5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine (MK-801) and 10,5-(Iminomethano)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene (IDDC)

โœ Scribed by Gee, Kyle R.; Lu, Yixin; Barmettler, Peter; Rhodes, Michael R.; Reddy, N. Laxma; Fischer, James B.; Cotter, Ronald E.; Weber, Eckard; Keana, John F. W.


Book ID
121315325
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
895 KB
Volume
59
Category
Article
ISSN
0022-3263

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Synthesis of 11C-labeled (ยฑ)-5-methyl-10
โœ Dale O. Kiesewetter; Ronald D. Finn; Kenner C. Rice; James A. Monn ๐Ÿ“‚ Article ๐Ÿ“… 1990 ๐Ÿ› Elsevier Science โš– 367 KB

The synthesis of C5 labeled (+-)-5-[11C]methyl-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten- 5,10-imine [(+-)-[11C]MK801] has been accomplished via alkylation of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclo-hepten-5,10-imine-N-t- butylformamidine [(+-)-5-des-methyl MK801 formamidine). The 11C labeling is ac