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BRCA1andBRCA2mutations in central and southern Italian patients

✍ Scribed by Laura Ottini, Cristina D'Amico, Cristiana Noviello, Salvatore Lauro…

Book ID
120701212
Publisher
BioMed Central
Year
2000
Tongue
English
Weight
126 KB
Volume
2
Category
Article
ISSN
1465-5411

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BRCA1 and BRCA2 mutations in breast/ovar
BRCA1 and BRCA2 mutations in breast/ovarian cancer patients from central Italy
✍ L. Stuppia; P. Di Fulvio; G. Aceto; S. Pintor; S. Veschi; V. Gatta; A. Colosimo; 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 112 KB 👁 2 views

We report on the screening of the entire BRCA1/BRCA2 coding sequence by SSCP, PTT, and direct sequencing in 68 Italian families with recurrent breast or ovarian cancer. For each investigated proband, the probability of being carrier of a BRCA1/BRCA2 mutation was evaluated using the BRCAPRO software.