BRCA1andBRCA2mutation predictions using the BOADICEA and BRCAPRO models and penetrance estimation in high-risk French-Canadian families

Application of BRCA1 and BRCA2 mutation

Application of BRCA1 and BRCA2 mutation carrier prediction models in breast and/or ovarian cancer families of French Canadian descent

✍ KK Oros; P Ghadirian; CM Maugard; C Perret; Y Paredes; A-M Mes-Masson; WD Foulke 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 220 KB

Evaluating the performance of the breast

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

✍ Fischer, Christine (author);Kuchenbäcker, Karoline (author);Engel, Christoph (au 📂 Article 📅 2013 🏛 BMJ Publishing Group 🌐 English ⚖ 172 KB

Evaluating the performance of the breast

Evaluating the performance of the breast cancer genetic risk models BOADICEA, IBIS, BRCAPRO and Claus for predicting BRCA1/2 mutation carrier probabilities: a study based on 7352 families from the German Hereditary Breast and Ovarian Cancer Consortium

✍ Fischer, Christine (author);Kuchenbäcker, Karoline (author);Engel, Christoph (au 📂 Article 📅 2013 🏛 BMJ Publishing Group 🌐 English ⚖ 172 KB

Variations in theNBN/NBS1gene and the ri

Variations in theNBN/NBS1gene and the risk of breast cancer in non-BRCA1/2French Canadian families with high risk of breast cancer

✍ Sylvie Desjardins; Joly Charles Beauparlant; Yvan Labrie; Geneviève Ouellette; I 📂 Article 📅 2009 🏛 BioMed Central 🌐 English ⚖ 885 KB

Genetic variants and haplotype analyses

Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families

✍ Sylvie Desjardins; Pascal Belleau; Yvan Labrie; Geneviève Ouellette; Paul Besset 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 214 KB 👁 1 views

## Abstract Our current understanding of breast cancer susceptibility involves mutations in the 2 major genes __BRCA1__ and __BRCA2__, found in about 25% of high‐risk families, as well as few other low penetrance genes such as __ATM__ and __CHEK2__. Approximately two‐thirds of the multiple cases fa

Evaluation of the Contribution of the Th

Evaluation of the Contribution of the Three Breast Cancer Susceptibility Genes CHEK2 , STK11 , and PALB2 in Non- BRCA1/2 French Canadian Families with High Risk of Breast Cancer

✍ Guénard, Frédéric; Pedneault, Christopher St-Laurent; Ouellette, Geneviève; Labr 📂 Article 📅 2010 🏛 Mary Ann Liebert 🌐 English ⚖ 432 KB