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BRCA1 transactivates the cyclin-dependent kinase inhibitor p27Kip1

✍ Scribed by Williamson, Elizabeth A; Dadmanesh, Farnaz; Koeffler, H Phillip


Book ID
110066655
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
275 KB
Volume
21
Category
Article
ISSN
0950-9232

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Cyclin dependent kinase inhibitor p27Kip
✍ Gang Wang; Richard Reisdorph; Robert E. Clark Jr.; Robin Miskimins; Ronald Linda πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 269 KB

## Abstract Expression of cyclin dependent kinase (Cdk) inhibitor p27^Kip1^, which blocks cell cycle progression from G~1~ to S phase, can be regulated via multiple mechanisms including transcription, protein degradation, and translation. Recently, it was shown that p27^Kip1^ plays an important rol