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Cyclin-dependant kinase inhibitors CIP1 (p21) and KIP1 (p27) in ovarian cancer

✍ Scribed by Annette Schmider-Ross; Olaf Pirsig; Elisabeth Gottschalk; Carsten Denkert; Werner Lichtenegger; Angela Reles

Publisher
Springer-Verlag
Year
2005
Tongue
English
Weight
272 KB
Volume
132
Category
Article
ISSN
1432-1335

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## Background and objectives: P27kip1 (p27) plays an important role as a negative regulator of cell cycle-dependent kinase activity during progression of the cell cycle. the most important prognosticator of breast cancer is nodal status, and the aim of this study was to determine the prognostic imp