BRCA1 Mutations in Familial Ovarian Cancer
β Scribed by Thomas A. Lallas; Thomas E. Buekers; Richard E. Buller
- Book ID
- 115639556
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 77 KB
- Volume
- 67
- Category
- Article
- ISSN
- 1096-7192
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Ovarian cancer is a clinically important cancer in Turkey. The contribution of BRCA1 and BRCA2 to ovarian cancer in Turkish patients has not previously been described. In this study we investigated the presence of BRCA1 and BRCA2 mutations in 102 consecutively ascertained, hospital-based, ovarian ca
Sixty high-risk breast and/or ovarian cancer families from North-Eastern Poland were screened for germline mutations in BRCA1 (MIM# 113705) and BRCA2 (MIM# 600185), using a combination of protein truncation test, denaturing high-performance liquid chromatography and direct sequencing. Sixteen (27%)