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Three novel BRCA1/BRCA2 mutations in breast/ovarian cancer families in Croatia

โœ Scribed by Sonja Levanat; Vesna Musani; Mirela Levacic Cvok; Ilona Susac; Maja Sabol; Petar Ozretic; Diana Car; Domagoj Eljuga; Ljerka Eljuga; Damir Eljuga


Book ID
116508759
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
646 KB
Volume
498
Category
Article
ISSN
0378-1119

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Novel germline mutations in the BRCA1 an
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The two major hereditary breast/ovarian cancer predisposition tumor suppressor genes, BRCA1 and BRCA2 that perform apparently generic cellular functions nonetheless cause tissue-specific syndromes in the human population when they are altered, or mutated in the germline. However, little is known abo