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BRCA1 and BRCA2 gene mutations in hereditary and sporadic ovarian cancer and the clinical implications

✍ Scribed by Samir A. Farghaly


Book ID
113985533
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
129 KB
Volume
179
Category
Article
ISSN
1097-6868

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In this study we genotyped Turkish breast/ovarian cancer patients for BRCA1/BRCA2 mutations: protein truncation test (PTT) for exon 11 BRCA1 of and, multiplex PCR and denaturing gradient gel electrophoresis (DGGE) for BRCA2, complemented by DNA sequencing. In addition, a modified restriction assay w