Composite tissue allotransplantation holds a great potential for providing increased knowledge of anatomy and microsurgical experience for life-enhancing reconstructions. Many transplant cases around the world have made this a clinical reality at the present time. Composite tissue allotransplants co
Bone marrow chimerism and transplantation tolerance
โ Scribed by Boris Nikolic; Megan Sykes
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 776 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0952-7915
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โฆ Synopsis
Bone marrow chimerism and transplantation tolerance
๐ SIMILAR VOLUMES
Background: Animals reconstituted with allogeneic whole bone marrow (WBM) are often tolerant of donor-specific solid organ grafts. Clinical application of bone marrow transplantation in solid organ transplantation has been limited, however, principally by graft-versus-host disease. We previously dem
Composite tissue allografts (CTAs) are currently accepted in the clinic; however, long-term immunosuppression is still needed for allograft survival. The presence of donor-specific chimerism may induce tolerance. Thirty-six vascularized bone marrow transplantation (VBMT) allotransplantation were per