Self-tolerance to host and donor following HLA-mismatched bone marrow transplantation

Minimum requirement of donor cells to re

Minimum requirement of donor cells to reduce the glycolipid storage following bone marrow transplantation in a murine model of Fabry disease

✍ Takayuki Yokoi; Hiroshi Kobayashi; Yohta Shimada; Yoshikatsu Eto; Nobuyuki Ishig 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 229 KB

## Abstract ## Background Fabry disease (FD) is a lysosomal storage disorders characterized by a deficiency of the lysosomal enzyme, α‐galactosidase A. This results in the accumulation of glycolipids, mainly globotriaosylceramide (GL‐3), in the lysosomes of various organs. Although bone marrow tra