๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Chimerism and bone marrow based therapies in transplantation

โœ Scribed by Maria Siemionow; Serdar Nasir

Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
155 KB
Volume
27
Category
Article
ISSN
0738-1085

No coin nor oath required. For personal study only.

โœฆ Synopsis

Composite tissue allotransplantation holds a great potential for providing increased knowledge of anatomy and microsurgical experience for life-enhancing reconstructions. Many transplant cases around the world have made this a clinical reality at the present time. Composite tissue allotransplants contain multiple tissue types, including bone, muscle, vessels, nerves, skin, and immune cells and bear a huge antigenic load. Although immunosuppressive drugs are applied successfully to prevent allograft rejection, their side effects pose a barrier to worldwide use. Bone marrow therapy in many tolerance induction protocols, therefore, provides a guide to reaching the target of permanent immunotolerance. Multiple studies suggest that bone marrow is immunomodulatory and may facilitate allograft acceptance. In this review, bone marrow based therapy protocols of clinical and experimental models are presented in two major categories: solid organ and composite tissue transplantation.

๐Ÿ“œ SIMILAR VOLUMES

Chimerism induction in vascularized bone
Chimerism induction in vascularized bone marrow transplants augmented with bone marrow cells
โœ Emrah Arslan; Aleksandra Klimczak; Maria Siemionow ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 499 KB

Composite tissue allografts (CTAs) are currently accepted in the clinic; however, long-term immunosuppression is still needed for allograft survival. The presence of donor-specific chimerism may induce tolerance. Thirty-six vascularized bone marrow transplantation (VBMT) allotransplantation were per

Renal function after conditioning therap
Renal function after conditioning therapy for bone marrow transplantation in childhood
โœ Patzer, Ludwig; Hempel, Lutz; Ringelmann, Felix; Misselwitz, Joachim; Fuchs, Die ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 169 KB ๐Ÿ‘ 2 views

The knowledge of renal function in the course of BMT is poor. We prospectively investigated glomerular and tubular function in 42 children who underwent BMT because of malignancy. Seventeen children were transplanted autologously. Investigations were performed before and immediately after the condit

Tube feeding and bone marrow transplanta
Tube feeding and bone marrow transplantation
โœ Hopman, G.D. ;Peรฑa, E.G. ;le Cessie, S. ;van Weel, M.H. ;Vossen, J.M.J.J. ;Meari ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 75 KB

## Abstract ## Background Children undergoing bone marrow transplantation (BMT) have poor oral intake during the transplant period, caused mainly by the intensive therapy used for their conditioning. Nutritional support (NS) is almost always needed. Whenever possible, tube feeding (TF) is preferre