The approximative estimation of the function μ([NH^+^~4~]) in cultures of __E. coli__ ML 30 had shown that bistability of the ammonium concentration in ammonium limited continuous cultures could be possible (BERGTER __et al.__ 1977). This phenomenon suggested a bistability in the regulation of ammon
Bistabilität der Pyruvatproduktion von Escherichia coli ML 30 in kontinuierlicher Kultur
✍ Scribed by Prof. Dr. F. Bergter; M. Roth
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 296 KB
- Volume
- 17
- Category
- Article
- ISSN
- 0233-111X
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✦ Synopsis
Abstract
The pyruvate production of E. coli ML 30 in continuous cultures was investigated. In a glucose mineralsalt medium with ammonium as the limiting substrate two stable stationary states (bistability) of pyruvate concentration were obtained. The bistability was limited to dilution rates lower than 0.3 h^−1^ and connected with a decrease of the yield coefficient (Y~Glc~) from ≈︁0.45 to ≈︁0.1.
📜 SIMILAR VOLUMES
## Abstract The transient behaviour of ammonium limited continuous cultures of __E. coli__ ML 30 led to the hypothesis that the bistability of pyruvate formation primarily is caused by a bistability of the ammonia metabolism. Therefore, a function μ([NH^+^~4~]) should be expected different from tha
## Abstract Recently bistability in the pyruvate production of ammonia‐limited glucose‐grown __Escherichia coli__ ML 30 chemostat cultures was evidenced. The present investigation shows that the state of higher pyruvate production is connected with a lower glycogen content than in cells in the stat