## Abstract Evidence is presented that cyclic AMP is engaged in the regulation of a bistability in the glucose and energy metabolism of NH~3~‐limited chemostat cultures of __Escherichia coli__ ML 30. Cyclic AMP probably reverses the repression of the citric acid cycle by glucose favouring the state
✦ LIBER ✦
Bistability in the glucose and energy metabolism of ammonia-limited chemostat cultures of Escherichia coli ML 30
✍ Scribed by Dr. P. J. Müller; Beate Von Frommannshausen
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 393 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0233-111X
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✦ Synopsis
Abstract
Recently bistability in the pyruvate production of ammonia‐limited glucose‐grown Escherichia coli ML 30 chemostat cultures was evidenced. The present investigation shows that the state of higher pyruvate production is connected with a lower glycogen content than in cells in the state of lower pyruvate production.
The results support the view of a regulation of bistability on the step of pyruvate consumption by the citric acid cycle.
Pronounced differences in energy formation in the two states of glucose bistability are discussed.
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