Bispecific antibodies in cancer therapy
β Scribed by David M Segal; George J Weiner; Louis M Weiner
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 58 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0952-7915
No coin nor oath required. For personal study only.
β¦ Synopsis
Abbreviations bsAb bispecific antibody
π SIMILAR VOLUMES
A review of the clinical trials of antibody based cancer therapies reveals that this approach can, in rare cases, induce complete remissions in individual patients with cancer. Since these trials have usually involved patients with large tumor masses, tumor cell inaccessibility is probably a major r
Abbreviations ADCC antibody-dependent cellular cytotoxicity BCR B cell antigen-receptor CCA cell-cycle arrest EGFR epidermal growth factor receptor FcR Fc receptor Id idiotype IFN-Ξ³ Ξ³ interferon Ξ³ mAb monoclonal antibody MAPK mitogen-activated protein