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Bispecific antibody and its clinical applications in cancer

✍ Scribed by Yuanfu Xu; Chunzheng Yang; Zhenping Zhu


Publisher
Springer
Year
2001
Tongue
English
Weight
708 KB
Volume
46
Category
Article
ISSN
1001-6538

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πŸ“œ SIMILAR VOLUMES


Bispecific antibodies in cancer therapy
✍ David M Segal; George J Weiner; Louis M Weiner πŸ“‚ Article πŸ“… 1999 πŸ› Elsevier Science 🌐 English βš– 58 KB

Abbreviations bsAb bispecific antibody

Preclinical and clinical data with bispe
✍ H.H van Ojik; T Valerius πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 199 KB

Bispecific antibodies constitute a novel approach to improve antibody efficacy. In vitro, constructs to recruit myeloid effector cells have been extensively investigated, and first animal data in human Fc receptor transgenic mice confirmed their promising therapeutic potential. Clinical experience w