Biosynthesis of macrolide antibiotics. 4. Stereochemistry of hydrogen labeling of brefeldin A by [2-2H3]acetate
β Scribed by Hutchinson, C. Richard; Kurobane, Itsuo; Cane, David E.; Hasler, Heinz; McInnes, A. G.
- Book ID
- 126107143
- Publisher
- American Chemical Society
- Year
- 1981
- Tongue
- English
- Weight
- 464 KB
- Volume
- 103
- Category
- Article
- ISSN
- 0002-7863
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## Abstract The four deuteriated 4βphenylbutyric [2,3β^2^H~2~]β, [4,4β^2^H~2~]β, [2,3,4,4β^2^H~4~]β, and [2,2,3,3,4,4β^2^H~6~]βacids have been synthesized in high isotopic purity by utilizing crossed Kolbe electrolysis of methyl hydrogen [^2^H~0~]β, [2,3β^2^H~2~], and [2,3,3,3β^2^H~4~]βsuccinates a