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Biosynthesis of 2-C-methyl-d-erythritol, a putative C5 intermediate in the mevalonate independent pathway for isoprenoid biosynthesis

โœ Scribed by Tore Duvold; Jean-Michel Bravo; Catherine Pale-Grosdemange; Michel Rohmer


Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
299 KB
Volume
38
Category
Article
ISSN
0040-4039

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Free 2-C-methyl-d-erythritol is utilised for isoprenoid biosynthesis by Escherichia coli mutants lacking the two ยฎrst enzymes of the methylerythritol phosphate pathway, the deoxyxylulose phosphate synthase and isomero-reductase. For feeding experiments, this tetrol was synthesised with an overall 43