Biomimetically inspired total synthesis of (12S)-12-hydroxymonocerin and (12R)-12-hydroxymonocerin
β Scribed by Fang, Bowen; Xie, Xingang; Jing, Peng; Zhao, Changgui; Li, Huilin; Ma, Haichen; She, Xuegong
- Book ID
- 121721435
- Publisher
- Elsevier Science
- Year
- 2013
- Tongue
- French
- Weight
- 410 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0040-4020
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π SIMILAR VOLUMES
The first total synthesis of (1 lR, 12s) diHETE IS reported. The key step is the highly chemioand stereaselective osmylation of a double bond in a trienyne system selectively complexed by an Fe(CO)3 group.
We recently reported a total synthesis of sesquifenchene2 from the key bicycle [2.2. llheptsnone derivative 3 and suggested at that time the possibility of utilizing 3 and derivatives thereof for construction
All chemical yields refer to chromatographically homogeneous products. All new compounds exibited satisfactory spectral (IR, NMR, and mass ) data.