Biomimetic Synthesis of Primary Enamides by Decarboxylation of α,β-Dehydroamino Acids
✍ Scribed by Prof. Dr. Ulrich Schmidt; Dr. Albrecht Lieberknecht
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 138 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Condensation of amides of Boc‐amino acids^3)^ with pyruvic acid leads to Boc‐dipeptides **1** – **3** of dehydroalanine and 1‐Boc‐5‐alkyl‐2‐methyl‐4‐oxo‐2‐imidazolidinecarboxylic acids **8** – **10**. The amides, however, do not condense with phenylpyruvic acid. Boc‐dipeptides of dehydr
Condensation or Zand TFA-amino acid amides with 2-0x0acids. namely butanoic, 3-methylbutanoic, 4-methylpcntanoic, and (3RS)-3-methylpentanoic acid yields (in the presence of p toluenesulfonic acid as a catalyst) Z-and TFA-dipeptides with C-terminal AAbu" (1 -4). AVal (5-8), ALeu (9-11). and AIle (12