BIOLOGY OF MAMMALIAN L1 RETROTRANSPOSONS
โ Scribed by Ostertag, Eric M.; Kazazian Jr, Haig H.
- Book ID
- 111898525
- Publisher
- Annual Reviews
- Year
- 2001
- Tongue
- English
- Weight
- 810 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0066-4197
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Transposable elements, and retroviral-like elements in particular, are a rich potential source of genetic variation within a host's genome. Many mutations of endogenous genes in phylogenetically diverse organisms are due to insertion of elements that affect gene expression by altering the normal pat
LINE-1 (L1) retrotransposons are replicating repetitive elements that, by mass, are the most-abundant sequences in the human genome. Over one-third of mammalian genomes are the result, directly or indirectly, of L1 retrotransposition. L1 encodes two proteins: ORF1, an RNA-binding protein, and ORF2,