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Binding of plant alkaloids berberine and palmatine to serum albumins: a thermodynamic investigation

โœ Scribed by Asma Yasmeen Khan, Maidul Hossain, Gopinatha Suresh Kumar


Book ID
120751309
Publisher
Springer
Year
2012
Tongue
English
Weight
539 KB
Volume
40
Category
Article
ISSN
0301-4851

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Binding of DNA-binding alkaloids berberi
โœ Md. Maidul Islam; Prateek Pandya; Sebanti Roy Chowdhury; Surat Kumar; Gopinatha ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 870 KB

The interaction of two natural protoberberine plant alkaloids berberine and palmatine with tRNA phe was studied using various biophysical techniques and molecular modeling and the data were compared with the binding of the classical DNA intercalator, ethidium. Circular dichroic studies revealed that