A thermodynamic approach to the binding mechanisms of cefotaxime to serum albumins
β Scribed by Gloria M. Fernandez; Jose M. Lumbreras; David Ordonez
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 459 KB
- Volume
- 82
- Category
- Article
- ISSN
- 0022-3549
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Binding sites on human serum albumin (HSA) for anionic drugs and fatty acids have been thermodynamically characterized by microcalorimetry. The binding and the thermodynamic parameters were directly computed from the calorimetric titration data at 37 "C in a phosphate buffer (pH 7.4) using one-and t
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