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Spectroscopic and Calorimetric Studies on the Binding of Alkaloids Berberine, Palmatine and Coralyne to Double Stranded RNA Polynucleotides

✍ Scribed by Islam, Md. Maidul; Chowdhury, Sebanti Roy; Kumar, Gopinatha Suresh


Book ID
120383502
Publisher
American Chemical Society
Year
2009
Tongue
English
Weight
326 KB
Volume
113
Category
Article
ISSN
0022-3654

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Binding of DNA-binding alkaloids berberi
✍ Md. Maidul Islam; Prateek Pandya; Sebanti Roy Chowdhury; Surat Kumar; Gopinatha πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 English βš– 870 KB

The interaction of two natural protoberberine plant alkaloids berberine and palmatine with tRNA phe was studied using various biophysical techniques and molecular modeling and the data were compared with the binding of the classical DNA intercalator, ethidium. Circular dichroic studies revealed that