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Binding characteristics of SSR180575, a potent and selective peripheral benzodiazepine ligand

✍ Scribed by V Vin; N Leducq; F Bono; J.M Herbert

Book ID
116287144
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
141 KB
Volume
310
Category
Article
ISSN
0006-291X

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## Abstract The synthesis of the [^3^H] labelled peripheral benzodiazepine receptor (PBR) ligand CB 34, useful for binding assay, tissue distribution studies, and elucidation of the physiological role of PBR, is described. Catalytic reduction with ^3^H~2~ gas and 10% Pd/C catalyst of the key interm