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Binding characteristics of [3H]DAA1106, a novel and selective ligand for peripheral benzodiazepine receptors

โœ Scribed by Shigeyuki Chaki; Takeo Funakoshi; Ryoko Yoshikawa; Shigeru Okuyama; Taketoshi Okubo; Atsuro Nakazato; Masashi Nagamine; Kazuyuki Tomisawa


Book ID
114017083
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
397 KB
Volume
371
Category
Article
ISSN
0014-2999

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## Abstract The synthesis of the [^3^H] labelled peripheral benzodiazepine receptor (PBR) ligand CB 34, useful for binding assay, tissue distribution studies, and elucidation of the physiological role of PBR, is described. Catalytic reduction with ^3^H~2~ gas and 10% Pd/C catalyst of the key interm