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Binding of [3H]CB 34, a selective ligand for peripheral benzodiazepine receptors, to rat brain membranes

✍ Scribed by M.Giuseppina Pisu; Giacomo Papi; Patrizia Porcu; Giuseppe Trapani; Andrea Latrofa; Giovanni Biggio; Mariangela Serra

Book ID
114014405
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
152 KB
Volume
432
Category
Article
ISSN
0014-2999

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Synthesis of the [3H] labelled potent an
Synthesis of the [3H] labelled potent and selective peripheral benzodiazepine receptor ligand CB 34
✍ A. Latrofa; G. Trapani; M. Franco; M.J. Harris; M. Serra; G. Biggio; G. Liso πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 French βš– 104 KB

## Abstract The synthesis of the [^3^H] labelled peripheral benzodiazepine receptor (PBR) ligand CB 34, useful for binding assay, tissue distribution studies, and elucidation of the physiological role of PBR, is described. Catalytic reduction with ^3^H~2~ gas and 10% Pd/C catalyst of the key interm