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Bicyclanes: V. New syntheses of cis-bicyclo[3.3.0]octane and cis-bicyclo[3.3.0]oct-2-ene

✍ Scribed by J. Knotnerus; Miss H. Schilling

Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
226 KB
Volume
83
Category
Article
ISSN
0165-0513

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Synthesis and stereochemical study of a
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The preparation of a modular antimalarial drug named trioxaquine containing a cis-bicyclo [3.3.0]octane-3,7-dione is reported. Two diastereomeric racemates have been separated and characterised by NMR. To cite this article: O. Dechy-Cabaret et al., C. R. Chimie 5 (2002) 297-302 Β© 2002 AcadΓ©mie des s