Bicyclanes IV. Preparation and properties of the methyl-cis-bicyclo[3.3.0]octanes
β Scribed by J. Knotnerus; Miss H. Schilling
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 652 KB
- Volume
- 83
- Category
- Article
- ISSN
- 0165-0513
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π SIMILAR VOLUMES
The preparation of a modular antimalarial drug named trioxaquine containing a cis-bicyclo [3.3.0]octane-3,7-dione is reported. Two diastereomeric racemates have been separated and characterised by NMR. To cite this article: O. Dechy-Cabaret et al., C. R. Chimie 5 (2002) 297-302 Β© 2002 AcadΓ©mie des s
## Abstract Alkylation of bicyclo[3.3.0]octaneβ2,8βdione (**1**), which is prepared by a modification of the procedure described in the literature, gives the methylβ and propynylβderivatives **6** and **7** (__Scheme 1__). In addition to the method described previously (__Scheme 2__), 9βmethylβ__ci
Our interest in the hydrocarbon tricyclo[3.3.0.0Jt7 Ioctane (l) has been stimulated by its bisnor relationship to adamantane (zero carbon bridges between C-l-C-5 and C-3-C-7 rather than one carbon bridges), its symmetry (Dad) and the fact that it contains the most twisted norbornane skeleton of reco