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Baker's yeast reduction of 4-hetero-2-(2-nitroethyl)cyclohexanones

✍ Scribed by Cristina Forzato; Patrizia Nitti; Giuliana Pitacco; Ennio Valentin

Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 584 KB
Volume: 8
Category: Article
ISSN: 0957-4166
DOI: 10.1016/s0957-4166(97)00191-2

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## Abstract Bioreduction of 3‐substituted‐2‐oxoal‐kanephosphonates by baker's yeast afforded 3‐substituted‐2‐hydroxy‐alkanephosphonates in moderate to good yields and ee value. These compounds could serve as useful chirons for the stereoselective synthesis of phosphorus analogs of biologically acti