✦ LIBER ✦

Azulene analogs of pharmacologic agents

✍ Scribed by Tully J. Speaker; Glenden D. Redman

Publisher: John Wiley and Sons
Year: 1966
Tongue: English
Weight: 255 KB
Volume: 55
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600550506

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Azulene analogs of pharmacologic agents II: Amides

✍ Peter H. Doukas; Tully J. Speaker 📂 Article 📅 1971 🏛 John Wiley and Sons 🌐 English ⚖ 299 KB

AbstractnThe paper describes the synthesis of nine azulene analogs of the benzenoid pharmacologic agent lidocaine, as part of a study of the pharmacodynamic effects of nonbenzenoid aromatic compounds. Two series of compounds were prepared: 1-azulyl amides and 1-amido-3-acetyl azulenes. Keyphrases 0

Azulene analogs of pharmacological agent

Azulene analogs of pharmacological agents III: Acute toxicity and local anesthetic activity of azulylamides and azulenecarboxamides

✍ P. H. Doukas; T. J. Speaker; R. S. Thompson 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 351 KB

Pharmacology of novel nicotinic analogs

✍ M. Imad Damaj; William Glassco; Malgorzata Dukat; Everett L. May; Richard A. Gle 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 992 KB

It is believed that nicotine exerts its psychoactive and addictive effects through neuronal nicotinic receptors (nAChRs). Surprisingly, few systematic structure-activity relationship (SAR) studies have been undertaken with nicotine. The major goal of our laboratory is to characterize the mechanisms

Antimuscarinic agents: Furan analogs of

Antimuscarinic agents: Furan analogs of benzilate esters

✍ James F. Stubbins; Patricia M. Hudgins; Dagmar C. Murphy 📂 Article 📅 1980 🏛 John Wiley and Sons 🌐 English ⚖ 456 KB

Difurocoumarins: Psoralen analogs as pho

Difurocoumarins: Psoralen analogs as photochemotherapeutic agents

✍ A. Chilin; P. Manzini; S. Caffieri; P. Rodighiero; A. Guiotto 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 53 KB

## Abstract New tetracyclic psoralen‐like compounds have been synthesized, which are characterized by two furan rings angularly condensed on the coumarin nucleus and are therefore called difurocoumarins. This structural feature may favour the intercalation into the DNA helix and then monofunctional

Antitumor agents II: Nitrogen analogs of

Antitumor agents II: Nitrogen analogs of mycophenolic acid

✍ J. A. Beisler; Sharon S. Hillery 📂 Article 📅 1975 🏛 John Wiley and Sons 🌐 English ⚖ 379 KB

Mycophenolic acid, a novel antibiotic of low toxicity containing no nitrogen atoms in its structure, induces tumor regression in several murine solid tumor assays. It has been reported in extensive structure-activity studies that chemical modifications on the antibiotic itself reduce or eliminate an