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Azulene analogs of pharmacologic agents II: Amides

✍ Scribed by Peter H. Doukas; Tully J. Speaker

Publisher: John Wiley and Sons
Year: 1971
Tongue: English
Weight: 299 KB
Volume: 60
Category: Article
ISSN: 0022-3549
DOI: 10.1002/jps.2600600335

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✦ Synopsis

AbstractnThe paper describes the synthesis of nine azulene analogs of the benzenoid pharmacologic agent lidocaine, as part of a study of the pharmacodynamic effects of nonbenzenoid aromatic compounds. Two series of compounds were prepared: 1-azulyl amides and 1-amido-3-acetyl azulenes.

Keyphrases 0 1-Azulyl amides (lidocaine analogs )-synthesis CJ 1-Amido-3-acetyl azulenes (lidocaine analogs)-synthesis 0 Lidocaine analogs-synthesis, I-azulyl amides, 1-amido-3-acetyl azulenes Column chromatography-separation 1 Analyses were performed by the Schwarzkopf Microanalytical

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