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Automated synthesis of 2′-deoxy-2′-[18F]fluoro-5-methyl-1-β-d-arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module

✍ Scribed by Zibo Li; Hancheng Cai; Peter S. Conti


Book ID
116799668
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
397 KB
Volume
38
Category
Article
ISSN
0969-8051

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📜 SIMILAR VOLUMES


Synthesis of [18F]-labeled 2′-deoxy-2′-f
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 1 views

## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th

A general synthesis of 2′-deoxy-2′-[18F]
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 French ⚖ 77 KB 👁 1 views

## Abstract Several 2′‐deoxy‐2′‐[^18^F]fluoro‐1‐__β__‐D‐arabinofuranosyluracil derivatives have been synthesized. Coupling of 1‐bromo‐2‐deoxy‐2‐[^18^F]fluoro‐3,5‐di‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** with protected uracil derivatives **3a–e** followed by hydrolysis and high‐performance liquid