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Evaluation of 2′-deoxy-2′-[18F]fluoro-5-methyl-1-β-l-arabinofuranosyluracil ([18F]-l-FMAU) as a PET imaging agent for cellular proliferation: comparison with [18F]-d-FMAU and [18F]FLT

✍ Scribed by Ryuichi Nishii; Andrei Y. Volgin; Osama Mawlawi; Uday Mukhopadhyay; Ashutosh Pal; William Bornmann; Juri G. Gelovani; Mian M. Alauddin


Publisher
Springer
Year
2007
Tongue
English
Weight
404 KB
Volume
35
Category
Article
ISSN
0340-6997

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Synthesis of [18F]-labeled 2′-deoxy-2′-f
✍ Mian M. Alauddin; Peter S. Conti; John D. Fissekis 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 100 KB 👁 1 views

## Abstract Synthesis of 2′‐deoxy‐2′‐[^18^F]fluoro‐5‐methyl‐1‐__β__‐D‐arabinofuranosyluracil ([^18^F]‐FMAU) is reported. 2‐Deoxy‐2‐[^18^F]fluoro‐1,3,5‐tri‐O‐benzoyl‐__α__‐D‐arabinofuranose **2** was prepared by the reaction of the respective triflate **1** with tetrabutylammonium[^18^F]fluoride. Th