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Automated determination of disopyramide and N-monodealkyldisopyramide in plasma by reversed-phase liquid chromatography with a column switching system

✍ Scribed by A. Del Cont Bernard; M.J. Royer Morrot; A. Zhiri; M. Rambourg; R.J. Royer


Book ID
103804050
Publisher
Elsevier Science
Year
1992
Weight
308 KB
Volume
574
Category
Article
ISSN
0378-4347

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## Abstract Melagatran is an active thrombin inhibitor showing oral and parenteral bioavailability for antithrombotic therapy. A simple and convenient liquid chromatographic method has been developed and applied to the analysis of melagatran in rabbit plasma. The clean‐up and separation of the samp