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Asymmetric reduction of the prochiral carbon-carbon double bond of methyl 2-chloro-2-alkenoates by use of fermenting bakers' yeast

✍ Scribed by Utaka, Masanori; Konishi, Satoshi; Mizuoka, Ami; Ohkubo, Toshiyasu; Sakai, Takashi; Tsuboi, Sadao; Takeda, Akira


Book ID
126120535
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
594 KB
Volume
54
Category
Article
ISSN
0022-3263

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Indium hydride (Cl 2 InH) generated in situ from a combination of a catalytic amount of indium(III) chloride and sodium borohydride selectively reduces the carbon carbon double bond in conjugated alkenes such as a,a-dicyano olefins, a,b-unsaturated nitriles, cyano esters, cyanophosphonate, diesters