Asymmetric Hydrocyanation of Hydrazones Catalyzed by Lanthanide−PYBOX Complexes
✍ Scribed by Keith, John M.; Jacobsen, Eric N.
- Book ID
- 125980805
- Publisher
- American Chemical Society
- Year
- 2004
- Tongue
- English
- Weight
- 75 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1523-7060
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📜 SIMILAR VOLUMES
Complexes formed between lanthanide trichlorides and 2,6-bis(substituted-2-oxazolin-2-yl)pyridine (pybox) ligands are effective catalysts for the enantioselective addition of trimethylsilylcyanide (TMSCN) to a range of aldehydes.
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## Abstract An indium complex of chiral pyridine bis(oxazoline) (PYBOX) has been applied to the catalytic asymmetric allylation of ketones. It has been found that this chiral indium complex is strong enough to promote the reaction of ketones with allyltributylstannane smoothly. The products were ob