Catalytic, asymmetric cyanohydrin synthesis mediated by lanthanide(III) chloride pybox complexes

✍ Scribed by Helen C. Aspinall; Nicholas Greeves; Peter M. Smith

• Book ID: 104260622
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 222 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(98)02685-9

✦ Synopsis

Complexes formed between lanthanide trichlorides and 2,6-bis(substituted-2-oxazolin-2-yl)pyridine (pybox) ligands are effective catalysts for the enantioselective addition of trimethylsilylcyanide (TMSCN) to a range of aldehydes.