## Abstract More than 80% of cells from a human promyelocytic leukemic cell line (HLβ60) possess the capacity for selfβrenewal as evidenced by their ability to form large primary colonies in semisolid medium and the presence within these colonies of cells capable of subsequent colony formation. Col
Asymmetric cell division in human leukemic promyelocytic cells (HL-60).
β Scribed by Tadao Matsuhisa
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 233 KB
- Volume
- 19
- Category
- Article
- ISSN
- 1065-6995
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β¦ Synopsis
Abstract
Small cells accounted for 8β9% of the human leukemic promyelocytic cells (HLβ60). The diameter of the small cells was 8.44 ΞΌm, whereas that of the large cells, which were heterogeneous in cell size, was 11.0 ΞΌm. The small cells were produced from the large cells through asymmetric cell division, which was demonstrated by cloning experiments and by microscopy.
π SIMILAR VOLUMES
## Abstract The recently established human promyelocytic cell line HLβ60 was induced to differentiate in the present of DMSO. During this process, physiochemical, and functional changes were detected simultaneously. After exposure to DMSO for more than 1 day, the cell volume decreased and the tende
Human promyelocytic leukemia (HL-60) cells display a novel voltage-dependent outward current under voltage clamp. This current is present at low levels in the proliferative state and in granulocytes derived from HL-60 cells which were induced to differentiate with retinoic acid. It is elevated in ma
Sodium dichromate [Cr(VI)] and cadmium chloride [Cd(II)] are both cytotoxic and mutagenic. This study examined the toxic and apoptotic potentials of these two cations on three cell types in vitro, namely, human chronic myelogenous leukemic (CML) K562 cells, promyelocytic leukemic HL-60 cells, and no