The catalytic asymmetric alkylation reaction of 0t-fluorotetralones promoted by a chiral quaternary ammonium salt derived from cinchonine under phase-transfer catalyzed conditions was described. The reaction proceeded smoothly to give the desired products with up to 91% ee. This methodology provides
β¦ LIBER β¦
Asymmetric Alkylation of Malonic Diester Under Phase-Transfer Conditions
β Scribed by Kanemitsu, Takuya; Koga, Shintaro; Nagano, Daisuke; Miyazaki, Michiko; Nagata, Kazuhiro; Itoh, Takashi
- Book ID
- 120401818
- Publisher
- American Chemical Society
- Year
- 2011
- Tongue
- English
- Weight
- 1021 KB
- Volume
- 1
- Category
- Article
- ISSN
- 2155-5435
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