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Association of variations in monoamine oxidases A and B with Parkinson's disease subgroups

โœ Scribed by A Parsian; B Racette; Z.H Zhang; M Rundle; J.S Perlmutter

Book ID
116981180
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
127 KB
Volume
83
Category
Article
ISSN
0888-7543

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Association of a monoamine oxidase B all
Association of a monoamine oxidase B allele with Parkinson's disease
โœ Janice H. Kurth; Dr. Matthias C. Kurth; Shirley E. Poduslo; John D. Schwankhaus ๐Ÿ“‚ Article ๐Ÿ“… 1993 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 685 KB

Monoamine oxidase B (MAO-B) is implicated in the cause of Parkinson's disease (PD) because of its role in metabolizing the neurotoxin l-methyl-4-phenyl-l,2,3,6-tetrahydropyridine, and forming H,02 during dopamine metabolism. Altered MAO-B activity has been observed in PD platelets. Polymerase chain