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Assessment of aniline derivatives-induced DNA damage in the liver cells of B6C3F1 mice using the alkaline single cell gel electrophoresis (‘comet’) assay

✍ Scribed by Barbara Przybojewska

Book ID
117469541
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
75 KB
Volume
147
Category
Article
ISSN
0304-3835

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Assessment of aniline derivatives-induced DNA damage in the liver cells of B6C3F1 mice using the alkaline single cell gel electrophoresis (“comet”) assay
✍ Barbara Przybojewska 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 28 KB 👁 2 views

The alkaline single cell gel electrophoresis (SCGE) or "comet" assay under alkaline conditions was used to measure DNA damage in the liver cells of B6C3F1 male mice exposed to 2,4-dimethylaniline and 2,4,6-trimethylaniline. Cells embedded in agarose were lysed, subjected briefly to an electric field