Assembly of DNA and protein during replication in HeLa cells
โ Scribed by SEALE, RONALD L.
- Book ID
- 109695380
- Publisher
- Nature Publishing Group
- Year
- 1975
- Tongue
- English
- Weight
- 538 KB
- Volume
- 255
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/255247a0
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The rate of DNA synthesis in HeLa S3 cells, as measured by incorporation of C14-labeled thymidine, is strongly dependent on protein synthesis at all times during the S phase. The relation between the rate of DNA synthesis and the rate of protein synthesis is linear when measured two or three hours a
increasing evidence has supported the concept that many of the enzymes and factors involved in the replication of mammalian DNA function together as a multiprotein complex. We have previously reported on the partial purification of a multiprotein form of DNA polymerase from human HeLa cells shown to