Assay of tissue levels of S-adenosylmethionine
β Scribed by Ross J. Baldessarini; Irwin J. Kopin
- Publisher
- Elsevier Science
- Year
- 1963
- Tongue
- English
- Weight
- 171 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0003-2697
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π SIMILAR VOLUMES
## Abstract This article describes the radiosynthesis of ^11^Cβlabelled Sβadenosylmethionine by an enzymatic process. This methyl donor was prepared by condensation of Lβ(methylβ^11^C) methionine with ATP. The synthesis and purification could be carried out in 20 minutes with a final yield of 80 %.
## Abstract For Abstract see ChemInform Abstract in Full Text.
In the biosynthesis of labeled S-adenosylmethionine and S-adenosylethionine from the corresponding 1"-labeled sulfur amino acids by yeast, some radioimpurity occurred by non-speci@ labeling of the sulfonium compounds. This is explained by partial degradation of methionine and ethionine in the yeast