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Assay of 6-thioinosinic acid and 6-thioguanine nucleotides, active metabolites of 6-mercaptopurine, in human red blood cells

✍ Scribed by Lynne Lennard


Publisher
Elsevier Science
Year
1987
Weight
737 KB
Volume
423
Category
Article
ISSN
0378-4347

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A rapid and sensitive high-performance l
✍ Lawrence E. Lavi; John S. Holcenberg πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 English βš– 635 KB

A highly sensitive and rapid assay for the detection of 6-mercaptopurine metabolites in the red blood cells-of leukemic patients receiving the drug has been developed. The method employs a batchchromatographic procedure using a mercurial cellulose resin to selectively absorb thiol compounds combined