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High-performance liquid chromatographic assay of the methyl and nucleotide metabolites of 6-mercaptopurine: quantitation of red blood cell 6-thioguanine nucleotide, 6-thioinosinic acid and 6-methylmercaptopurine metabolites in a single sample

โœ Scribed by Lynne Lennard; Helen J. Singleton


Publisher
Elsevier Science
Year
1992
Weight
440 KB
Volume
583
Category
Article
ISSN
0378-4347

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A rapid and sensitive high-performance l
โœ Lawrence E. Lavi; John S. Holcenberg ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 635 KB

A highly sensitive and rapid assay for the detection of 6-mercaptopurine metabolites in the red blood cells-of leukemic patients receiving the drug has been developed. The method employs a batchchromatographic procedure using a mercurial cellulose resin to selectively absorb thiol compounds combined