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Aryl radical cyclisation on to a pyrrole nucleus

โœ Scribed by Keith Jones; Tim C.T. Ho; James Wilkinson

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
311 KB
Volume
36
Category
Article
ISSN
0040-4039

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๐Ÿ“œ SIMILAR VOLUMES

Evidence on the nature of cobalt-mediate
Evidence on the nature of cobalt-mediated aryl radical cyclisations
โœ Andrew J. Clark; Keith Jones ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 209 KB

## Regiochemical and stereochemical evidence is presented which indicates that cobalt-mediated aryl radical cyclisations involve simple free radicals. Radical cyclisatton reactions have achieved considerable importance in synthetic chemistry'.

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โœ Andrew J. Clark; Keith Jones ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 567 KB

Abstmct: A synthesis of the te&ahydrofuro[2,3-blindole (3) in 6 step from 4-methoxyaniline involving a key cobalt-mediated aryl radical cycliin is presented. This hetuucycle is a known, late intermediate. in the synthesis of the alkaloid physovenine (2).

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โœ Karen Goodall; Andrew F. Parsons ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 252 KB

The 5-endo radical cyclisation of pyruvic acid derived dehydroalanines which contain chiral ester auxiliaries is reported. Cyclisation of the menthol ester derivative using Bu3SnH at 80ยฐC proceeded with low diastereoselectivity (1.