## Regiochemical and stereochemical evidence is presented which indicates that cobalt-mediated aryl radical cyclisations involve simple free radicals. Radical cyclisatton reactions have achieved considerable importance in synthetic chemistry'.
Cobalt-mediated aryl radical cyclisations: A formal synthesis of physovenine
β Scribed by Andrew J. Clark; Keith Jones
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- French
- Weight
- 567 KB
- Volume
- 48
- Category
- Article
- ISSN
- 0040-4020
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β¦ Synopsis
Abstmct: A synthesis of the te&ahydrofuro[2,3-blindole (3) in 6 step from 4-methoxyaniline involving a key cobalt-mediated aryl radical cycliin is presented. This hetuucycle is a known, late intermediate. in the synthesis of the alkaloid physovenine (2).
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