𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Approaches to the regiospecific synthesis of Anthracycline antibiotics

✍ Scribed by Jack E. Baldwin; Algis J. Rajeckas

Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
438 KB
Volume
38
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Regiospecific synthesis of linear quinon
Regiospecific synthesis of linear quinone systems: efficient convergent synthesis of anthracycline intermediates
✍ Kathlyn A. Parker; James L. Kallmerten πŸ“‚ Article πŸ“… 1979 πŸ› Elsevier Science 🌐 French βš– 236 KB

The antineoplastic activity and challenging structural features of the anthracycline antibiotics have caused extensive efforts to be directed toward their chemical synthesis. 2 In particular, Adriamycin (la) and daunomycin (lb) have become the focus of much attention. excellent contributions in thi

Regiospecific synthesis of 11-desoxyanth
Regiospecific synthesis of 11-desoxyanthracycline antibiotics starting with aloe-emodin
✍ J. Alexander; D.L. Flynn; L.A. Mitscher; T. Veysoglu πŸ“‚ Article πŸ“… 1981 πŸ› Elsevier Science 🌐 French βš– 207 KB

The regiospecific synthesis of an established ll-desoxyanthracycline synthon ($) from aloe-emodin (3a) is described. The contemporary search for analogues of the anthracycline antitumor antibiotics daunomycin' and doxorubicin2 is intense. Particularly desired is the development of analogues retainin

A short, efficient synthesis of an anthr
A short, efficient synthesis of an anthracycline antitumor antibiotic synthon
✍ Jose Alexander; L.A. Mitscher πŸ“‚ Article πŸ“… 1978 πŸ› Elsevier Science 🌐 French βš– 189 KB

Synthetic approaches to the anthracyclines related to adriamycin-daunomytin are of great interest because of the relative costliness of the agents and their useful clinical properties against a relatively broad spectrum of tumors? Of the presently available syntheses, those based upon the Diels-Ald